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Wonder Drug Phenylpiracetam Seems to Benefit All

Guide to Phenylpiracetam Including Benefits, Dosing, and Availability of the Drug

Who wouldn’t want to be smarter and more athletic if they had the choice?  In today’s world, information is everything.  Those that retain and process the most information will have an obvious advantage over others.  We all have our limitations, but more and more discoveries like the smart drug phenylpiracetam may start to help us overcome these limitations and allow our species to advance further.  Phenylpiracetam is becoming one of the more popular “nootropics”, or smart drugs, that are also gaining popularity by the day due to their apparent ability to protect the brain, improve memory, creativity, and offer other general cognitive enhancements.


In previous generations, a person’s hands might have been considered the most important body part, allowing them to defend themselves, build shelters, hunt/gather, etc., but the majority of us would probably consider our brains a more important body part today.   From the time we wake up in the morning, we’re rushed to work and forced to organize all of our thoughts and plan all of our tasks.  We get into our offices and strategize innovative ways to beat our competition.  Society constantly has us thinking about how to approach friends, colleagues, family, or potential customers.  Because our minds are constantly running haywire, Phenylpiracetam proves to be a very beneficial supplement for the modern-day thinker.  The drug also offers benefits to the elderly, those with brain trauma and cognitive decline, as well as those with severe mental diseases.  Below are some of the most common characteristic effects that the drug phenylpiracetam has to offer:

  • Antidepressant
  • Antipsychotic
  • Anticonvulsant
  • Antianxiolytic
  • Anti-amnesic
  • Myoclonus treatment
  • Parkinson’s Disease Treatment
  • Child Autism Treatment
  • Fatigue Treatment (general stimulant)

What is Phenylpiracetam?


Phenylpiracetam is a chemical that was discovered in 1983 by a scientist in Russia.  It is a member of the Racetam drug family and is a phenylated analog of the drug piracetam which was heavily studied by the Russians decades ago and still remains the subject of many studies today.  Unfortunately, many of the Russian studies are not available to the Western world of medicine, but its popularity and interests by the Russians have made others just as curious if not more.  Phenylpiracetam’s brand names are Phenotropil and Carphedon, both of which are prescription drugs and prescribed for many conditions in many countries around the world.  There are also hundreds of cognitive enhancement supplements that include the drug, available on the internet.

Phenylpiracetam was derived from its cousin, piracetam.  Piracetam was the first discovered racetam drug and was the most studied out of the racetam drug family.  Piracetam was originally discovered in the 60’s in Belgium, but did not receive a lot of attention until the Russians got ahold of it and found some of its amazing benefits/uses.  It was this Russian intrigue that led to the creation of Phenylpiracetam which is piracetam with a phenyl branch added to the compound.  Phenylpiracetam has greater liquidity than piracetam, meaning it is better absorbed by fats/oils, which makes it more bioavailable.  This extra bioavailability requires a much lower dose of the drug to achieve the same results.  Phenylpiracetam has also seems to be more stimulating than regular piracetam which is neither a stimulant or depressant.


How does Phenylpiracetam work and what is it used for?

Like most drugs, we’re not 100% sure how its mechanisms of action work because we do not fully understand how each part of the brain works and how it will react to foreign substances.  However, there are several theories that have been verified with studies to suggest accurate mechanism of actions.  Double-blind placebo studies can be expensive and without a large pharmaceutical company paying for these studies, many deserving studies remain unconducted. So, there is still much to learn about this promising drug.  The popularity of the substance and the low risk for adverse side effects has led to the use and experimentation of thousands of people.  Many of these people post their experiences with the drug on the internet.  Most users seem to have at least some positive effects from using the smart drug.

One of the most common uses for phenylpiracetam is the use for neuroprotection and use as a general cognitive enhancer.  Phenylpiracetam and other racetam drugs have shown to increase the amount of fluid in brain cell membranes which increases mitochondrial output of the cells.  Think of all of the times you have heard how important it is to stay hydrated. When your cells become dehydrated, they do not perform at peak performance and some cells may actually die off if not properly hydrated.  Phenylpiracetam basically keeps the brains cells extra-hydrated, allowing them to operate at peak performance.  The drug has also shown to be a positive allosteric modulator of the AMPA receptor and is believed to act on the brain’s ion channels which increase neuronal excitability.  Again, this is another mechanism that increases the general output of our brain cells.  Most drugs that have this ability come with many unwanted side effects like nervousness, anxiety, jitters, etc., but phenylpiracetam typically manages to do so without causing these effects.  In fact, as we’ll discuss later, the drug often reverses the effects of anxiety in most users.

Phenylpiracetam is also prescribed to stroke patients that display cognitive decline.  One reason that phenylpiracetam is thought to have a positive impact on stoke patients is because the drug increases blood flow to the brain, delivering more oxygen.  However, it is still unknown if the increased blood flow is a primary effect of the drug or if it is a side effect caused by the increase of brain activity.  Most strokes, such as ischemic strokes, are caused by parts of the brain not receiving enough blood flow or oxygen, causing the cells to die off.  It is thought that phenylpiracetam helps deliver blood to these areas where the victim had the stroke.  When a person has a stroke, it is typically a long recovery process if they’re even able to recover.  The brain doesn’t grow back to its previous state, but studies have shown that the brain exhibits a degree of plasticity, meaning that other brain cells may be able to learn how to operate similar to their neighboring cells and can take over their tasks if needed.  It is presumed that phenylpiracetam’s positive effects are primarily from delivering blood to the part of the brain that was deprived of oxygen, but it is unclear if it also has a positive effect on the brain’s plasticity as well.

Phenylpiracetam is often used to help treat those with Alzheimer’s disease or organic cognitive decline with aging.  Alzheimer’s disease is an incurable disease that affects a person’s memories.  After onset, the disease typically worsens quickly until the individual no longer remembers friends, family, tasks, etc.  While phenylpiracetam’s neuronal excitability/output and increase blood flow probably contribute to the positive effects seen by those with Alzheimer’s, the drug has also shown to increase the use of an abundant neurotransmitter in our brains called acetylcholine.  Acetylcholine has been proven to be a very important contributor to our memory processes.

Conducting studies on phenylpiracetam, scientists have shown that the drug acts as an anti-amnesiac, allowing those with forgotten memories caused by trauma to remember certain things.  One of the common side effects of a benzodiazepine drug is memory problems/difficulties.  Phenylpiracetam has also shown to help those with lost memories caused by this benzodiazepine side effect.  Not only that, but studies with mice have shown to reverse much of the depressant effects of benzodiazepine drugs, while not affecting their anxiolytic benefits.

Phenylpiracetam has also shown to have positive psychomotor effects in humans and is being studied as a possible treatment to those with Parkinson’s disease.  For those that aren’t aware of the horrible disease, it is caused by nerve cell damage that triggers a response causing dopamine levels to drop very low.  Some common symptoms of Parkinson ’s disease are slow movements, muscle stiffness, loss of balance and motor control.   Choline and acetylcholine not only impact our memory, but also play a part in motor function and muscle movements which probably contribute to the positive impact of the disease.  Phenylpiracetam is not only being studied and being prescribed for Parkinson’s disease, but is also commonly prescribed as an anticonvulsant.

Phenylpiracetam has shown to act as a mild norepinephrine reuptake inhibitor which likely contributes to its stimulating effects.  The drug has been used to treat those with fatigue.  The World Anti-Doping Agency added it to their banned list of stimulant drugs due to its stimulating effects, positive effects on mental and psychomotor responses, and its odd ability to allow the body to better handle extreme cold temperatures, prevention of hypoxia, and increased resistance to stress.

Not only does phenylpiracetam act as a norepinephrine reuptake inhibitor, but evidence suggests that it may also act as a dopamine reuptake inhibitor, which would make the drug a NDRI (norepinephrine dopamine reuptake inhibitor).  These characteristics of the drug likely contribute to some of the anti-depressant effects that seen with its use.  Phenylpiracetam has shown to benefit those with sleeping disorders.  The increased extracellular dopamine levels from phenylpiracetam use are most likely what is responsible for this benefit of the drug.

There is also evidence to suggest that the miracle drug, phenylpiracetam, may boost motivation in individuals.  The motivation increase is likely caused by the elevation in both dopamine and norepinephrine levels since both of these neurotransmitters are typically responsible for feelings of well-being and motivation.  After all, depleted levels of these chemicals thought to be the main cause of attention-deficit disorder (ADHD) and may cause distraction of day-to-day tasks.  The most common treatment for ADHD is stimulant drugs, such as amphetamines or methylphenidate.  Both drugs boost neurotransmitters like serotonin, epinephrine, and dopamine.  These drugs often guide the brain to determine what’s important to focus on, store memories of, or to filter out/not pay attention to.  However, these drugs often come with adverse side effects that outweigh the benefits of the drug.  Many of these side effects include increase heart rate, increased blood pressure, mood changes, lack of impulse control, anxiety, paranoia, and sleep disorders.  These unwanted side effects may make phenylpiracetam a favorable drug to the typical stimulants prescribed for ADHD.  In a study conducted with rats, the rats that were given phenylpiracetam showed work outputs of 350%, while the rats given amphetamines had a work output of 150% and rats given methylphenidate had an output of 170%.

Racetam drugs are a derived from the neurotransmitter GABA.  However, GABA Receptors and GABA metabolism do not seem to be directly affected by racetams.  Phenylpiracetam seems to have both anti-epileptic and anti-anxiolytic properties.  It is unclear how the drug helps those with seizures, but it is thought to have something to do with the relation to GABA since GABA stimulation often helps those that suffer from epilepsy.  The anti-anxiolytic effects could in part be related to GABA as well.  GABA slows down the firing of neurons in the brain, often resulting in relaxation or depression of the Central Nervous System.  The increased levels of dopamine may also assist in the reduction of anxiety in individuals.

There are also many other interesting properties that phenylpiracetam and drugs of the Racetam family seem to possess.  Studies suggest that racetams promote alpha brain waves when ingested.  There are four types of brain waves that our brains emit that correspond with our mental state/brain activity.  Alpha brain waves are the type of waves that are emitted when we’re in our deepest and most active thoughts while remaining relaxed and thinking clearly.  Another interesting study has shown that racetams may promote interhemispheric connectivity, meaning that our left-brain and right-brain hemispheres communicate more.  This may allow us to generate creative thoughts with a logical touch.  Some left brain-dominant users have suggested that racetam use allows them to think more creatively and some have even described experiences such as seeing colors much brighter than usual after taking a dose of a racetam.

Is Phenylpiracetam Safe?

Amazingly, this wonder drug proves to be one of the safest drugs available.  One reason it remains to be a chemical of interest to many scientists around the world is because of the apparent safety of the drug and lack of side effects, while being able to provide substantial benefits – especially to many that suffer from life-destroying diseases.  Many drugs that are prescribed to those with diseases like Alzheimer’s or Parkinson’s come with very intrusive side effects or risks that can be more dangerous than the actual disease itself.  However, since all humans are different, there are always some individuals that will react differently to a chemical than the general population.  While adverse side effects are somewhat rare in the use of phenylpiracetam, some of the most common side effects that have been reported with phenylpiractam use include headaches, upset stomach, insomnia, increased anxiety, solumnance, weight gain, and general weakness.

Phenylpiracetam is usually taken in doses of 100mg – 200mg, 1 to 3 times daily.  General suggestions state not to exceed 750mg per day because there seem to be no added benefits when ingesting doses larger than this.  By taking more than 750mg per day, you’re basically only increasing your chances of unwanted side effects.  100mg seems to be the most common and most effective single dose.  While the lethal dose of phenylpiracetam in humans is unknown, there have been no reports of phenylpiracetam overdoses.  Studies in rats show that racetam drugs have an extremely low acute toxicity, meaning that it would take an incredibly large amount of the drug to cause toxic effects or poisoning of the body.

Phenylpiracetam is often combined with other supplements and cognitive enhancers by those who frequently use smart drugs.  Many claim to be able to reach their desired state of mind and focus with a stack consisting of certain smart drugs, which often include phenylpiracetam.  Because these smart drugs are not extremely powerful or intoxicating, and since they’re generally ingested in low doses, instances of adverse side effects due to drug interactions are uncommon.  However, caution should always be used when combining any kind of drug. It is important to research all drug combinations to ensure that the drugs to not potentiate/negate each other, or create a chemical byproduct when processed by the liver that may be harmful to the body.

Phenylpiracetam Availability

While phenylpiracetam is a prescription drug in many countries around the world, it is not a prescription drug in most western countries like the United States.  In the United States, it has not been evaluated or approved by the FDA and is not allowed to be sold in the U.S., but there are many suppliers that sell the drug online.  This is common with drugs that are not patented or sold by Big Pharma companies.  Whether they like to admit it or not, the FDA is an entity of the U.S. Government which is ultimately a privatized business.  Without receiving funding or a commission of sales, they’re not likely to study, evaluate, monitor, or allow sales of a chemical unless being rewarded appropriately for doing so – unless, of course, the drug is harming many people or being abused.  In the instance of harm, they would likely label the drug a controlled substance.

I was a member of a forum back when nootropics first started gaining popularity, where we had open discussions about chemicals of interest pertaining to life extension and cognitive enhancement.  Racetams gained a lot of attention quickly during those days.  Several suppliers started providing the smart drug at an affordable price and sales seemed to be booming.  The largest supplier in the U.S. was also a member of our forum.  He couldn’t have been happier with his quick success.  He was researching as much as possible to find other safe smart drugs that he could manufacture and provide the public.  And then it came – a letter from the FDA demanding that he seize all sales of Piracetam from any business that he owned in the United States.  A couple of the other large suppliers also received these letters around the same time and they stopped selling to U.S. citizens.  Many of the smaller suppliers continued production and sales because they knew that if they stayed under a certain amount of sales, they would sail under the FDA’s radar.  There are still many suppliers today that are producing phenylpiracetam and other cognitive enhancers that have not yet been approved by the FDA and selling them to people in the U.S. from the U.S.  However, to my knowledge all of the businesses are online-based businesses.  I have not yet seen phenylpiracetam or any other racetams being sold in an actual retail store.


In summary, phenylpiracetam seems to be quite an amazing and promising drug.  It provides benefits to students that need a kick of motivation, focus, and memory enhancement.  The drug may also be useful in treating some of the worst diseases humans encounter like Alzheimer’s and Parkinson’s.  Phenylpiracetam seems to safely offer everybody some type of benefit or relief.  I have taken this drug at times throughout the last decade and will continue to do so as long as it’s available.  If you think that the smart drug may benefit you in some way, you may want to give it a try while it’s still obtainable.  I am almost certain that it will continue to be heavily studied by the scientific community as well as by the general public and I’m almost certain that additional findings and benefits will continue to surface in years to come.

Written by pbsawyer

I strive to educate the general population on non-common subjects to allow them to make educated decisions. Passion for neuroscience and non-conventional treatments.

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